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Faculty, University of Wisconsin School of Medicine and Public Health
Dr. Salih received her medical training at the University of Khartoum in the Sudan, completed an internship and residency at the Royal College of Obstetrics and Gynecology in the United Kingdom, completed another residency at Yale New Haven Hospital and served a fellowship at the University of Texas Medical Branch.
Dr. Salih specializes in a variety of infertility and reproductive endocrinology testing and treatments, as well as treatment for reproductive endocrine disorders such as polycystic ovary syndrome (PCOS), endometriosis, female hirsutism, hyperprolactinemia and amenorrhea.
| UW Health Clinics |
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Generations Fertility Care
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 (608) 265-0300
(800) 323-8942
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UW Hospital and Clinics
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Map
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| Languages Spoken |
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English
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Medical interpreters are available to help
patients communicate with hospital and clinic staff.
For more information, please contact
interpreter services at (608) 262-9000.
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Professional Certifications and Education
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| Board Certification |
Obstetrics & Gynecology
Reproductive Endocrinology & Infertility
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| Fellowship |
University of Texas Medical Branch, Galveston, TX
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| Residency |
Yale New Haven Hospital, CT
Royal College of Obstetrics and Gynecology, United Kingdom
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| Internship |
Royal College of Obstetrics and Gynecology, United Kingdom
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| Medical School |
University of Khartoum, Sudan, 1990
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Hospital Affiliations
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| Primary Affiliation(s) |
University of Wisconsin Hospital and Clinics
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| Secondary Affiliation(s) |
St. Mary's Hospital, Meriter Hospital
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| Research |
Dr. Salih's research seeks to identify mechanisms to improve fertility and reproductive health outcomes in female patients. In particular, she is investigating the molecular mechanisms and signaling pathways that are involved in gametogenesis, folliculogenesis and early embryonic development. Advanced age, genetic factors, environmental toxins and exposure to chemo- and radiations therapy lead to perturbed follicular developments. This translates into poor oocyte quality and interferes with the orderly and intricate process of oocyte maturation, ovulation, fertilization, and early embryonic development, thus culminating into poor reproductive outcome.
Dr. Salih is currently looking at the following aspects of human reproduction:
- Germ cell differentiation and development: Identifying factors that regulate gametogenesis, folliculogenesis, oocyte development and maturation, and early embryonic development by utilizing computer bioinformatics and sequence alignment programs to identify genes that are essential in reproduction in other model organisms and that may play a role in human reproduction.
- Derivation of germ cells and gametes from induced pluripotent stem cells (iPSc): Dr. Salih is currently studying the feasibility of utilizing stem cell-derived germ cell and gametes as a model system to elucidate key factors that are essential for gametogenesis, folliculogenesis, and early embryonic development.
- Fertility preservation in cancer patients: Dr. Salih is working to identify the MDR1 phenotype and signaling pathways that could lead to molecular shielding of the ovary from chemotherapy and radiation therapy. The ultimate goal will be to identify therapies that could molecularly shield the ovary against toxins.
- Estrogen metabolites and estrogen metabolizing enzymes in the human endometrium: Dr. Salih studying the effects of estrogen metabolites in relation to endometrial carcinogenesis and perturbed embryonic implantation.
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